To Spray or Not to Spray Fungicide on Corn for Grain or Silage?

Damon L. Smith, Extension Field Crops Pathologist, University of Wisconsin-Madison

Treating field corn, for grain, with fungicide has become a common practice in the Midwest. With so many fungicide programs and formulations, and the re-emergence of yield-limiting corn diseases, like northern corn leaf blight (NCLB) and gray leaf spot (GLS), foliar fungicide application has demonstrated an ability to reduce foliar disease severity and increase grain yield under some circumstances.

Figure 2: A computer simulation of 5% NCLB severity on a corn leaf.

Figure 1: A computer simulation of 5% NCLB severity on a corn leaf.

How do I know if disease is active at the time I want to spray?  While I hate talking about threshold levels for managing disease, it can be helpful in your decision making process to know what might be severe. While scouting look in the lower portion of the canopy. If some foliar disease symptoms are present in the lower canopy, make a visual estimation of how frequent (percentage of plants with lesions) the disease is in a particular area and how severe (how much leaf area is covered by lesions).  The lower leaves aren’t responsible for much yield accumulation in corn, but spores produced in NCLB and GLS lesions on these leaves can be splashed up to the ear leaves where disease can be very impactful. So by scouting the lower canopy and getting an idea of how much disease is present, you can “predict” what might happen later on the ear leaves to make an informed spray decision. The other consideration you should make while scouting is the resistance rating that the hybrid has for NCLB and/or GLS. If it is rated as resistant, then NCLB or GLS severity might not be predicted to get very severe, while in a susceptible hybrid, NCLB or GLS might be present on 50% or more of plants at high severity levels. Note however, that even if a hybrid is rated as resistant, it can still get some disease. Resistance isn’t immunity! If NCLB is present on at least half the plants and severity is at least 5-10% and weather is forecast to be rainy and cool, a fungicide application will likely be needed to manage the disease. So what does 5% leaf severity look like? Figure 1 is a computer generated image that shows 5% of the corn leaf with NCLB lesions. You can use this image to train your brain to visually estimate how severe the disease might be on a particular leaf. As for fungicide choice and timing, I consider that further below.

What fungicide should I spray and should I spray at all? My question is what are you trying to do? Control a disease or simply boost grain yield? Fungicide should be used as a tool to control a disease and preserve yield. There is no silver bullet fungicide out there for all corn diseases. However, there are many products which work well on a range of diseases. The Corn Fungicide Efficacy table lists products that have been rigorously evaluated in university research trials across the country. You can see there are several products listed that perform well on both NCLB and GLS. So obviously, if a disease is present and you are trying to control the disease, you might expect more return on your investment, compared to simply spraying fungicide and hoping that there might be a yield increase.

Paul et al. (2011) conducted research to investigate the return on investment (ROI) of using fungicide at low and elevated levels of disease. Data from 14 states between 2002 and 2009 were used in the analysis. They looked at 4 formulations of fungicide products across all of these trials. I won’t go into detail about all products, but will focus on one here, pyraclostrobin. This is the active ingredient in Headline® Fungicide. In all, 172 trials were evaluated in the analysis and Paul et al. found that on average there was a 4.08 bu/acre increase in corn grain yield when pyraclostrobin was used. So there does appear to be some increase in yield with the use of fungicide, but in our current market, will this average gain cover the fungicide application?


Figure 2. Break-even scenarios for corn when foliar fungicide was applied.

The suggested application rate for Headline® Fungicide is 6 to 12 fl oz/acre. My latest cost sheets indicate that at the 6 fl oz/acre rate, the cost of the product alone would be about $12/acre. Note that this does not include the custom applicator cost. This is a variable expense that would need to be added in to get an accurate ROI for your operation. Today we can estimate that we might sell corn grain somewhere between $3 and $4 per bushel. We can then use the cost of the fungicide product and the price of grain to figure out how many bushels of corn we need to make in the crop that would be treated with pyraclostrobin vs. not treating. Figure 2 is a table with various corn prices along the vertical axis and fungicide costs per acre along the horizontal axis. The cells indicate the bushels of corn per acre needed to break even when using a fungicide at the corresponding cost and corn grain sale price. Using the above scenario, we see that with corn priced between $3 and $4 per acre and a fungicide application cost of $between$10 and $15/acre, we would need to gain 2.5 – 5.0 bushels per acre when using Headline® Fungicide in the current corn market. Obviously these calculations are for just one product, but you can do the same for your farm and fungicide program and use the table to figure out what break-even yield gain you will need to cover your costs.

What are the odds of getting that 2.5 to 5 bushel per acre yield gain when using Headline® Fungicide? Paul et al. went further and calculated the probability of return at various corn prices and fungicide costs. They did separate analyses for foliar disease severity less than 5% and greater than 5%. In our current corn market with around $3/bu corn prices and a cost of Headline® Fungicide at $15/acre (fungicide plus custom application), Paul et al. found that at low foliar disease levels (<5% severity) the odds of a positive ROI using the fungicide would be around 50%. The odds of a positive ROI improve if disease severity is greater than 5%. In their calculations with higher levels of disease (>5% severity), the odds of a positive ROI would be between 60% and 70%. The morale of this story is that if you are going to use fungicides on corn, they should be targeted toward fields that will have, or are at risk, for disease!

So what about fungicide application timing? One of the best times to apply fungicide to maximize any benefits for grain corn is during tasseling (VT) and into the silking (R1-R2) timing. In multiple site-year studies across the corn belt of the U.S., application of fungicide on grain corn at VT resulted in over a 7 bu average yield gain. In Wisconsin, the average at the VT timing is about 5.5 bushels. However, this level of yield gain only materializes when a yield limiting foliar disease is active and moving up the canopy. You can check out results of the fungicide trials and the performance of various products over the last few years in Wisconsin by visiting my Fungicide Test Summaries page.

Finally, be aware that in some cases, application of fungicide in combination with nonionic surfactant (NIS) at growth stages between V8 and VT in hybrid field corn can result in a phenomenon known as arrested ear development. The damage is thought to be caused by the combination of NIS and fungicide and not by the fungicide alone. To learn more about this issue, you can CLICK HERE and download a fact sheet from Purdue Extension that covers the topic nicely. Considering that the best response out of a fungicide application seems to be between VT-R2, and the issues with fungicide plus NIS application between V8 and VT, I would suggest holding off for any fungicide applications until at least VT.

What about fungicide on corn for silage? This practice has been gaining increased interest over the last several years. Dr. Felipe Cardoso’s animal science laboratory at the University of Illinois has published several peer-reviewed papers describing the physiological changes in the corn plant treated with several fungicides, that result in improved feed quality. In those studies yield was often not directly impacted by the fungicide application, but fibrous changes in the corn plant improved feed conversion to milk production in cows fed silage corn treated with fungicide.

Figure 3. Ear rot of corn.

Another possible benefit to treating both silage corn and grain corn with fungicide is the potential reduction in mycotoxin accumulation. Mycotoxins are secondary metabolites produced by fungi. There are 400-500 different known mycotoxins. In corn in Wisconsin, we typically are most concerned with deoxynivalenol (DON or vomitoxin) and fumonisins. These mycotoxins are produced by fungi in the group Fusarium which can cause ear rot issues (Fig. 3) and also stalk rot issues in corn. Recent studies by colleagues in Ontario, Canada have demonstrated that the triazole containing fungicide Proline (active ingredient: prothioconazole) applied at R1 (silking), or shortly after the beginning of silking, can reduce DON levels in corn grain, compared to not treating. The Field Crops Pathology Laboratory at the University of Wisconsin-Madison set out to determine if Proline, and other fungicides and programs, had a similar effect on silage corn treated with fungicide.

Our trial was established at the Arlington Agricultural Research Station located in Arlington, WI in 2017. The brown midrib (BMR) corn hybrid ‘P0956AMX’ was chosen for this study. Corn was planted on 11 May and chopped on 13 Sep. Single applications of various fungicide products (Table 1) were applied at growth stages V6 (19 Jun), R1 (26 Jul), 5 days post R1 (31 Jul), and 10 days post R1 (4 Aug). Ear rot severity was assessed by visually rating five ears per plot on the day of harvest. Yield was determined by harvesting the center two rows of each plot using a small plot silage chopper with an onboard platform weigh system. Chopped sub-samples were collected from each plot and analyzed for deoxynivalenol (DON) content.

Consistent with other datasets, we found no significant difference in yield across treatments (Table 1). Likewise, little difference in quality could be found among all treatments. This could be due to the fact that we started with a high-quality BMR hybrid, thus not readily responding to physiological changes that correspond to increased feed quality when treated with fungicide.

All fungicide treatments resulted in a significant reduction in DON content compared to the non-treated control, except Delaro applied at V6 and Quilt Xcel applied at R1. Application of the experimental 1 fungicide applied at R1 resulted in the lowest DON content among treatments. Remaining treatments had comparable DON levels to experimental 1 except for Quilt Xcel at R1. These results were consistent with previous data from Canada indicating that there is a “sweet spot” of application timing (especially when using Proline), when the goal is to reduce DON. The window of application begins at R1 (silking) and ends around 10 days after the start of R1.

Additionally, our data have shown that the product Quilt Xcel does not reduce DON levels on par with some other products. In fact, in other trials, Quilt Xcel has resulted in higher levels of DON in grain corn. In grass crops like wheat, it has been shown that products containing the strobilurin fungicide class can increase DON levels over not treating. Therefore, these products are not recommended for application after flowering in wheat. This same phenomenon could be possible in corn. Thus, care should be taken when choosing products and programs specifically aimed at reducing DON levels in corn silage.  


As we approach the critical time to make decisions about in-season disease management on corn, it is important to consider all factors at play while trying to determine if a fungicide is right for your corn operation. Here is what you should consider:

1) Corn hybrid disease resistance score – Resistant hybrids may not have high levels of disease which impact yield.

2) Get out of the truck and SCOUT, SCOUT, SCOUT – Consider how much disease and the level of severity of disease present in the lower canopy prior to tassel.

3) Consider weather conditions prior to, and during, the VT-R2 growth stages – if it is cool and wet, disease may continue to increase in corn and a fungicide application might be necessary. If it turns out to be hot and dry, disease development will stop and a fungicide application would not be recommended.

4) Consider your costs to apply a fungicide and the price you can sell your corn grain – Will you gain enough out of the fungicide application to cover its cost?

5) Hold off with making your fungicide application in Wisconsin until corn has reached the VT-R2 growth stages – The best foliar disease control and highest likelihood of a positive ROI will occur when fungicide is applied at VT when high levels of disease are likely.

6) Dairy farmers should think about the overall goal of using fungicide on silage corn. If the goal is to simply alter the corn plant physiologically to improve feed quality, there are numerous products and application timings that have the potential to provide a benefit over not treating. However, if the goal is to target mycotoxins, specifically DON, certain fungicide products may need to be applied specifically during the short silking stage (R1-R2) of the corn plant, to reduce DON levels.

7) Be aware that every time you use a fungicide you are likely selecting for corn pathogen populations that will become resistant to a future fungicide application – Make sure your fungicide application is worth this long-term risk. To learn more about fungicide resistance, you can CLICK HERE to download a UW Extension fact sheet.

Other Resources

Wisconsin Field Crops Fungicide Information Page

Applying Fungicides to Corn Early in Iowa


Haerr, K.J., Lopes, N.M., Pereira, M.N., Fellows, G.M., and Cardoso, F.C. 2015. Corn Silage from corn treated with foliar fungicide and performance of Holstein cows. J. Dairy Sci. 98:8962-8972.

Kalebich, C.C., Weatherly, M.E., Robinson, K.N., Fellows, G.M., Murphy, M.R., and Cardoso, F.C. 2017. Foliar fungicide (pyraclostrobin) application effects on plant composition of a silage variety corn. Animal Feed Science and Technology. 225:38-53.

Paul, P. A., Madden, L. V., Bradley, C. A., Robertson, A. E., Munkvold, G. P., Shaner, G., Wise, K. A., Malvick, D. K., Allen, T. W., Grybauskas, A., Vincelli, P., and Esker, P. 2011. Meta-analysis of yield response of hybrid field corn to foliar fungicides in the U.S. Corn Belt. Phytopathology 101:1122-1132.

White, D.G., editor. 2010. Compendium of Corn Diseases. APS Press.


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  1. […] Gray leaf spot is cause by a fungus named Cercospora zeae-maydis. During times of very warm temperature and high humidity (greater than 90%), GLS can increase rapidly on susceptible hybrids. In fields with large amounts of corn residue (e.g. corn-on-corn rotation, minimal tillage, etc.) GLS may be more prominent due to higher levels of inoculum. Symptoms start as small narrow, blocky lesions that might be tan in the center and have a darker margin (Fig. 1). Lesion can increase in size and number and will typically move from lower leaves to upper leaves. Yield loss is most prominent when lesions reach the ear leaves either 2 weeks before tasseling or two weeks after tasseling. Currently, in Wisconsin, we have seen few fields where lesions have reached the ear leaves prior to brown silk. However, in a small number of fields planted to a susceptible hybrid, there has been rapid increase to the ear leaves prior to tassel. In those fields a fungicide application may result in adequate yield protection to cover the cost of fungicide application. See my previous article on how to make the decision to spray fungicide on corn. […]

  2. […] How do I know if disease is active at the time I want to spray? While I hate talking about threshold levels for managing disease, it can be helpful in your decision making process to know what might be severe. While scouting look in the lower portion of the canopy… (read more) […]

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